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Mephedrone is a monoamine releasing Spion. It is a chiral compound and both of its enantiomers display similar potency as substrates at dopamine transporters. R-Mephedrone is much less potent than S-mephedrone as a substrate at serotonin transporters.[45]Mephedrone may be quantitated hinein blood, plasma or urine by gas chromatography-mass spectrom